https://www.getpeptidewise.com Comprehensive, evidence-based educational resource about peptides. Explore mechanisms of action, research, benefits, and safety profiles. en-us Tue, 14 Apr 2026 23:46:12 GMT https://www.rssboard.org/rss-specification https://www.getpeptidewise.com/peptides/bpc-157/ https://www.getpeptidewise.com/peptides/bpc-157/ BPC-157 is a synthetic pentadecapeptide derived from a protective protein found in gastric juice. It has been extensively studied in animal models for its remarkable tissue-healing properties across multiple organ systems. healing-recovery Mon, 13 Apr 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/tb-500/ https://www.getpeptidewise.com/peptides/tb-500/ TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring protein found in virtually all human and animal cells. It is studied for its role in actin regulation, wound healing, angiogenesis, and inflammation modulation. healing-recovery Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/kpv/ https://www.getpeptidewise.com/peptides/kpv/ KPV is a tripeptide derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH). It is studied primarily for its potent anti-inflammatory and gut-healing properties, particularly in models of inflammatory bowel disease. healing-recovery Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/ll-37/ https://www.getpeptidewise.com/peptides/ll-37/ LL-37 is the only human cathelicidin antimicrobial peptide, naturally produced by neutrophils, epithelial cells, and other immune cells. It plays dual roles in host defense (antimicrobial activity) and tissue healing, and is studied for wound repair, immunomodulation, and anti-biofilm properties. healing-recovery Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/epithalon/ https://www.getpeptidewise.com/peptides/epithalon/ Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland peptide Epithalamin. It is one of the most studied peptides for longevity and anti-aging effects, primarily through its ability to activate telomerase and elongate telomeres. anti-aging Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/ghk-cu/ https://www.getpeptidewise.com/peptides/ghk-cu/ GHK-Cu is a naturally occurring copper-binding tripeptide (Glycine-Histidine-Lysine) found in human plasma. It has been extensively studied for its roles in wound healing, skin regeneration, anti-aging effects, and gene expression modulation, with over 4,000 genes reportedly influenced by its activity. anti-aging Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/ss-31/ https://www.getpeptidewise.com/peptides/ss-31/ SS-31 (Elamipretide) is a synthetic mitochondria-targeted peptide that selectively concentrates in the inner mitochondrial membrane where it binds cardiolipin. It is studied for its ability to improve mitochondrial function, reduce oxidative stress, and protect against age-related and disease-driven mitochondrial dysfunction. anti-aging Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/semax/ https://www.getpeptidewise.com/peptides/semax/ Semax is a synthetic heptapeptide derived from ACTH (adrenocorticotropic hormone) developed in Russia. It is registered as a drug in Russia and Ukraine for cognitive enhancement, neuroprotection, and stroke treatment. It is studied for BDNF upregulation, memory enhancement, and anxiolytic effects. cognitive Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/selank/ https://www.getpeptidewise.com/peptides/selank/ Selank is a synthetic heptapeptide analog of the immunomodulatory peptide tuftsin, developed in Russia. It is registered as a drug in Russia for anxiety disorders and is studied for its anxiolytic, nootropic, and immunomodulatory properties with a favorable side effect profile. cognitive Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/dihexa/ https://www.getpeptidewise.com/peptides/dihexa/ Dihexa is a small molecule peptide analog derived from Angiotensin IV, developed at Washington State University. It is studied as an extraordinarily potent cognitive enhancer, reportedly seven orders of magnitude more potent than BDNF in facilitating synaptogenesis, with potential applications for neurodegenerative diseases. cognitive Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/cjc-1295/ https://www.getpeptidewise.com/peptides/cjc-1295/ CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) modified with Drug Affinity Complex (DAC) technology to extend its half-life from minutes to days. It stimulates pituitary GH secretion and is studied for muscle growth, fat loss, and recovery. performance Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/ipamorelin/ https://www.getpeptidewise.com/peptides/ipamorelin/ Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. It is one of the most selective GH-releasing peptides available, stimulating GH release without significant effects on cortisol or prolactin — making it a preferred choice in performance and anti-aging research protocols. performance Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/mk-677/ https://www.getpeptidewise.com/peptides/mk-677/ MK-677 (Ibutamoren) is an orally active, non-peptide growth hormone secretagogue that mimics ghrelin and stimulates GH and IGF-1 release. Unlike injectable GH peptides, it is taken orally and provides sustained GH elevation. It is studied for muscle growth, bone density, and metabolic effects. performance Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/bpc-157-tb-500/ https://www.getpeptidewise.com/peptides/bpc-157-tb-500/ The BPC-157 + TB-500 combination ("healing stack") pairs two of the most studied healing peptides with complementary mechanisms. BPC-157 promotes angiogenesis and tissue repair via VEGF/FAK pathways; TB-500 promotes cell migration and angiogenesis via actin regulation. Together they are studied for enhanced musculoskeletal healing and recovery. healing-recovery Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/thymosin-alpha-1/ https://www.getpeptidewise.com/peptides/thymosin-alpha-1/ Thymosin Alpha-1 is a 28-amino acid peptide derived from thymosin fraction 5 of the thymus gland. It is an approved pharmaceutical drug in approximately 35 countries for hepatitis B, hepatitis C, and immune-compromised conditions, making it one of the few peptides with robust clinical validation for immune modulation. immune Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/aod-9604/ https://www.getpeptidewise.com/peptides/aod-9604/ AOD-9604 is a synthetic fragment of human growth hormone (hGH), specifically the C-terminal region (amino acids 176–191). Unlike full GH, AOD-9604 retains GH's fat-metabolizing properties without affecting blood glucose or IGF-1 levels, making it a more targeted weight management research compound. weight-management Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/pt-141/ https://www.getpeptidewise.com/peptides/pt-141/ PT-141 (Bremelanotide) is an FDA-approved melanocortin receptor agonist used for hypoactive sexual desire disorder (HSDD) in premenopausal women. It is the only FDA-approved drug specifically for female sexual dysfunction and works through the central nervous system rather than vascular mechanisms. sexual-health Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/dsip/ https://www.getpeptidewise.com/peptides/dsip/ DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide first identified in 1974 from rabbit thalamic venous blood. It is named for its ability to induce delta (slow-wave) sleep activity in animal models and is studied for sleep quality, stress response, and neuroendocrine modulation. sleep Sun, 29 Mar 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/vk2735/ https://www.getpeptidewise.com/peptides/vk2735/ VK2735 is an investigational dual GLP-1/GIP receptor agonist developed by Viking Therapeutics. Phase 2 trials demonstrated substantial weight loss; Phase 3 maintenance dosing enrollment was completed in January 2026. weight-management Fri, 03 Apr 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/retatrutide/ https://www.getpeptidewise.com/peptides/retatrutide/ Retatrutide (LY3437943) is an investigational triple agonist developed by Eli Lilly that simultaneously activates GIP, GLP-1, and glucagon receptors. Phase 2 clinical data demonstrated 24.2% mean body weight reduction at the highest dose over 48 weeks — the highest weight loss reported for any investigational obesity drug at that stage. Phase 3 TRIUMPH trials are ongoing as of April 2026. weight-management Tue, 14 Apr 2026 00:00:00 GMT https://www.getpeptidewise.com/peptides/mots-c/ https://www.getpeptidewise.com/peptides/mots-c/ MOTS-c is a 16-amino acid peptide encoded within the 12S rRNA region of mitochondrial DNA. Unlike nuclear-encoded peptides, it is a naturally occurring mitochondria-derived peptide (MDP) that activates AMPK, improves insulin sensitivity, and acts as an exercise mimetic in animal models. A 2025 Nature study expanded its research profile into neuroprotection and pancreatic islet senescence. RFK Jr. announced on February 27, 2026 that MOTS-c is among peptides expected to return to FDA Category 1 compoundable status; formal rule publication is pending as of April 2026. anti-aging Tue, 14 Apr 2026 00:00:00 GMT